The Anti-HFE Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody to HFE. This antibody recognizes Human antigen. The Anti-HFE Mouse mAb Antibody has been validated for the following applications: Immunocytochemistry, and Western Blot.
Description
Entrez Summary: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.?